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Medications during pregnancy

Medications during pregnancy


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Question:

- The last menstruation was on February 9, 2007, then I was treated for helicobacter pilory for which I was given the following drugs: zentel, amoxicillin, fromilid and ultop. I started the treatment on February 14, 2007. About the time of February 20-22, 2007, I became pregnant. My question would be: what can this treatment harm the pregnancy?

Answer:


Zentel is a broad spectrum anthelmintic, used to treat parasites. Because albendazole has been shown to be embryotoxic and teratogenic in rats and rabbits, its use in pregnant women or those with suspected pregnancy is contraindicated.
For women of childbearing age (15-40 years), Zentel should be administered within the first 7 days after the onset of normal menstruation. So, regarding the administration of this product, there is a risk of fetal development, but the degree of impairment can only be determined by the doctor.
Amoxicillin is a bactericidal antibiotic with a spectrum comprising grampositive (except penicillinase) and gram-negative (E. coli, Pr. Mirabilis, Salmonella, etc.) germs. After oral administration the product is rapidly absorbed (70-80%) without being influenced by nutrition (it can be administered before, during or after meals) and achieves a maximum plasma concentration after about 2 hours, being completely metabolized in about 12-14 hours.
This product does not negatively influence the development of pregnancy, being one of the few antibiotics whose administration is allowed in pregnancy.
Formilide is the basic product clarithromycin whose administration is also prohibited in pregnancy and Ultop is actually omeprazole, administration of this product has not identified toxic effects on pregnancy or teratogenic effects.
Dr. Ciprian Pop-Began
- Obstetrics and Gynecology - Clinical Hospital of Obstetrics-Gynecology Prof. Dr. Panait Sarbu

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